Enhancing the Performance of Pressure Regulation via Genetic Algorithm (GA) for Negative Pressure Wound Therapy (NPWT) System

Authors

  • Tan Tian Swee Department of Biomedical Engineering and Health Sciences, Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia
  • Jahanzeb Sheikh ᵃDepartment of Biomedical Engineering and Health Sciences, Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia; ᵇDepartment of Biomedical Engineering, Sir Syed University of Engineering and Technology, Pakistan
  • Hira Zahid Department of Biomedical Engineering, Ziauddin University, Karachi, Pakistan
  • Sidra Agha Abid Department of Biomedical Engineering, Sir Syed University of Engineering and Technology, Pakistan
  • Muhammad Jawad Shafique Department of Biomedical Engineering, Sir Syed University of Engineering and Technology, Pakistan
  • Maheza Irna Binti Salim Department of Biomedical Engineering and Health Sciences, Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia
  • Ooi Jin Kiak Department of Biomedical Engineering and Health Sciences, Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia
  • Muhammad Kashif Shaikh Department of Software Engineering, Sir Syed University of Engineering and Technology, Pakistan
  • Michael Loong Peng Tan Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia

DOI:

https://doi.org/10.11113/mjfas.v21n3.4226

Keywords:

Control system, fuzzy logic, genetic algorithm, negative pressure wound therapy.

Abstract

Hard-to-heal wounds, such as diabetic foot ulcers, have become a significant healthcare concern with the rising incidence of diabetes. Negative Pressure Wound Therapy (NPWT) has shown advantages over traditional wound management methods, but the classical NPWT controllers have issues with unstable pressure generation and occasional injury. To address this, fuzzy logic has been integrated into NPWT systems to enhance performance. However, fuzzy controllers have limitations due to uncertainty and inconsistency in system design. This study hybridizes a genetic algorithm (GA) with the fuzzy NPWT system to improve negative pressure regulation stability. Comparative performance evaluations showed that GA-fuzzy NPWT reduced the mean steady-state error by 56.60%, increased the rise time by 10.31%, and reduced overshoot by 4.92%. However, the integration of GA also led to an increase in standard deviation, improving accuracy but raising variability in the system.

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Published

12-06-2025