Phytochemical investigation of noni (Morinda citrifolia L.) leaves extract applicated for sunscreen product
Keywords:Antimelanogenesis, flavonoid, noni
Morinda citrifolia L. (Noni) is an annual plant, distributed in the tropical parts of the world. Chemical constituents such as flavonoids, alkaloids, terpenoids, sterols, and minerals have been isolated from this plant. The pharmacological properties, based on scientific research, claimed as antibacterial, antiulcerogenic, anti-inflammatory, antioxidant, and especially for antimelanogenesis therapy. Iridoid, a flavonoid compound, is the main component found in the Noni leaves extract. Screening of Noni leaves extract possessed flavonoid and steroid content with the concentration of 2.82% and 0.14%, respectively. Therefore, the Noni leaves extract was potential used for sunscreen, based on antimelanogenesis activity.
Deng, S., West, B. J., Palu, A. K., Jensen, C. J. 2012. Phytochemical, antioxidant and toxicological investigation of Morinda citrifolia L. blossoms. International Scholarly Research Network, ISRN Analytical Chemistry, Article ID 160871.
Krishnaiah, D., Nithyanandam, R., Sarbatly, R. 2012. Phytochemical constituents and activities of Morinda citrifolia L. In Rao, V. (Ed.), Phytochemicals – A Global Perspective of Their Role in Nutrition and Health (pp 127–150), Intech.
Ramesh, S., Radhakrishnan, M., Anburaj, A., Elangomathavan, R., Patharajan, S. 2012. Physicochemical, phytochemical, and antimicrobial studies on Morinda citrifolia L. fruits at different maturity stages. International Journal of Pharmacy and Pharmaceutical Sciences, 4(5), 473–476.
Singh, D. R. 2012. Morinda citrifolia L. (Noni): A review of the scientific validation for its nutritional and therapeutic properties. Journal of Diabetes and Endocrinology, 3(6), 77–91.
Nivas, D., Gaikwad, D. K., Chavan, P. D. 2010. A review on ethnobotanical and medicobiological applications of Genus Morinda. Inventi Rapid: Ethnopharmacology, 2(1), 1–11.
Zin, Z. M., Hamid, A. A, Osman, A. 2002. Antioxidative activity of extracts from mengkudu (Morinda citrifolia L.) root, fruit and leaf. Food Chemistry, 78, 227–231.
Akihisa, T., Seino, K., Kaneko, E., Watanabe, K., Tochizawa, S., Fukatsu, M., Banno, N., Metori, K., Kimura, Y. 2010. Melanogenesis inhibitory activities of iridoid-, hemiterpene-, and fatty acid-glycosides from the fruits of Morinda citrifolia (Noni), Journal of Oleo Science, 59(1), 49–57.
Matsuda, H., Masuda, M., Murata, K., Abe, Y., Uwaya, A. 2013. Study of the anti-photoaging effect of noni (Morinda citrifolia). In Duc, G. H. T. (Ed.) Melanoma - From Early Detection to Treatment (pp 629–648), Intech.
Masuda, M., Itoh, K., Murata, K., Naruto, S., Uwaya, A., Isami. F., Matsuda, H. 2012. Inhibitory effects of Morinda citrifolia extract and its constituents on melanogenesis in Murine B16 melanoma cells. Biological & Pharmaceutical Bulletin, 35(1), 78–83.
Nagaveni, K., Parameswari, S., Angala, Gopinath, 2013, Standardization and phytochemical screening of methanolic extract of Ocimum sanctum Linn leaves. International Journal of Advances in Pharmaceutical Research, 4(8), 2167–2174.
Maleš, C., Šari, D., Boji, M. 2013. Quantitative determination of flavonoids and chlorogenic acid in the leaves of Arbutus unedo L. using thin layer chromatography. Journal of Analytical Methods in Chemistry, Article ID 385473.
Shah, R. K., Yadav, R. N. S. 2015. Qualitative phytochemical analysis and estimation total phenols and flavonoids in leaf extract of Sarcochlamys pulcherrima. Global Journal of Bio-Science and Biotechnology, 4(1), 81–84.
Stobiecki, M., Kachlicki, P. 2006. Isolation and identification of flavonoid. In Grotewold, E. (Ed.) The Sciences of Flavonoid (pp 47–50), Springer.
El-Olemy, M., Al-Muhtadi, F., Afifi, A. 1994. Experimental phytochemistry. A laboratory manual. Riyadh: College of Pharmacy, King Saud University.
Harborne, J. B. 1987. Metode Fitokimia. Bandung: Institut Teknologi Bandung.
Jaber, B. M., Jasim, S. F. 2014. Phytochemical study of stigmasterol and β-sitosterol in Viola odorata plant cultivated in Iraq, Iraqi Journal of Biotechnology, 13(2), 86–94.
Mo, S., Dong, L., Hurst, J., Breemen, R. B. 2013. Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography–Tandem mass spectrometry. Lipids, 48, 949–956.
Mohammad, A., Moheman, A. 2011. TLC/HPTLC in biomedical applications. In Srivastava, M. (Ed.) High-Performance Thin-Layer Chromatography (pp 152–155), Springer.
Saxena, R., Sharma, R., Nandy, B. C., Jasuja, N. D. 2014. Qualitative and quantitative estimation of bioactive compound in Mimosa hamata. International Journal of Pharmacy and Pharmaceutical Sciences, 6(6), 72–75.