Association between Cervix Intraepithelial Neoplasia (CIN) and High-Risk Human Papillomavirus (HPV) Genotypes in Iraqi Women


  • Mina M. Allos ᵃDepartment of Molecular and Medical Biotechnology, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq; ᵇDepartment of Applied Sciences, University of Technology, Baghdad, Iraq
  • Hassan M. Naif ᵃDepartment of Molecular and Medical Biotechnology, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq; ; ᶜDepartment of Medical Laboratories Technology, College of Health and Medical Technology, AlShaab University, Baghdad, Iraq



High-Risk Human Papilloma virus; Genotyping; premalignant cervical lesion; Cervical Cancer; Iraq women


Human Papillomavirus (HPV) is an oncogenic virus that primarily causes premalignant and malignant cervical lesions particularly infection with high-risk types of viruses. Cervical cancer (CC) is a common gynecological tumor, ranking second in the female reproductive system tumor, particularly in women from developing countries. The prevalent and genotyping of high-risk HPV among Iraqi women during various stages of cervical lesions and cervical cancer were examined by using a real-time PCR. Results of this work revealed that the prevalence of HPV infection in women suffering from gynecological problem was 43%. The distribution of the high-risk HPV was relatively high for both HR-HPV-16 (44.90%) and HR-HPV-39 (14.29%), with HR-HPV-16 is being the most common. The finding of this study can be used to manage HPV infection and cervical cancer particularly at earlier stages of cervical lesions.  


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