Kinetic modelling and extraction of Orthosiphon stamineus stems and leaves by SC-CO2


  • Nicky Rahmana Putra Faculty of Chemical and Energy Engineering, Universiti Teknologi Malayia, 81310 Johor Bahru,Malaysia
  • Ahmad Hazim Abdul Aziz
  • Zuhaili Idham
  • Dwila Nur Rizkiyah
  • Jumakir Jumakir
  • Muhammad Haziq Almar Mastaza
  • Mohd Azizi Che Yunus



Orthosiphon stamineus, supercritical carbon dioxide, extraction rate, antioxidant activity, modelling


The aims of this study are to determine the effect of parameters on the extraction yield of Orthosiphon stamineus stems and leaves extract and to examine the mass transfer process by kinetic models to obtain the extraction rate of supercritical carbon dioxide. Other objective is to compare the antioxidant activity of Orthosiphon stamineus stems and leaves extract using supercritical carbon dioxide extraction and Soxhlet extraction.Extraction parameters involved were pressure (10 and 30 MPa) and temperature (40 and 80 °C). DPPH method was used to examine the antioxidant activity of extract. A better correlation of kinetic mass transfer data has successfully fitted using Brunner model compared with Esquivel model with 6.09% average AARD and 0.992 coefficient of determination. The extraction rate of Orthosiphon stamineus leaves and stems were found to be in the rage of 0.52 × 10−3 to 8.84 × 10−3 g/min and 0.8160.52 × 10−3 to 8.816 × 10−3 g/min, respectively. The maximum antioxidant activity of Orthosiphon stamineus stems and leaves extract were 91.58% and 88%. Similarity in the quality for both extract of Orthosiphon stamineus stems and leaves makes the separation to be unnecessary.

Author Biography

Nicky Rahmana Putra, Faculty of Chemical and Energy Engineering, Universiti Teknologi Malayia, 81310 Johor Bahru,Malaysia



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