Anti-oxidant and anti-bacterial activities of Anthurium plowmaniileaves extracts

Authors

  • Nurina Rizka Ramadhania Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)
  • Fajriah Harun Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)
  • Adi Setyo Purnomo Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)
  • Sri Fatmawati Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)

DOI:

https://doi.org/10.11113/mjfas.v15n2.1040

Keywords:

Anthurium plowmanii, ABTS, DPPH, antibacteria, antioxidant

Abstract

Different solvent extracts of Anthurium plowmanii leaves were assayed for antioxidant and antibacterial activities. Methanol extract had the highest inhibition of DPPH and ABTS scavenging activities among extracts. Concentrations of methanol extract required for 50% inhibition of DPPH radical scavenging effect were recorded as 231,59 μg/mL. The IC50 of methanol and water extracts on ABTS were 57,23 μg/mL and 73,35 μg/mL, respectively. The lower IC50 values denotes a more potent antioxidant.   Dichloromethane and n-hexane extracts showed faint antibacterial activity against bacteria Pseudomonas aeruginosa and Bacillus subtilis was evaluated by broth dilution method. The results demonstrated great potential of the A. plowmanii leaves as a new source of new antioxidant agents.

Author Biographies

Nurina Rizka Ramadhania, Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)

Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia

Fajriah Harun, Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)

Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia

Adi Setyo Purnomo, Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)

Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia

Sri Fatmawati, Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS)

Department of Chemistry, Faculty of Natural Sciences, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia

References

Alam, Md. N., Bristi, N. J., and Rafiquzzaman, Md. 2013. Review on in vivoand in vitro methods evaluation of antioxidant activity. Saudi Pharmaceutical Journal, 21 (2), 143-152.

Arias, M. E., Gomez, J. D., Cudmani, N. M., Vattuone, M. A., and Isla, M. I. 2004. Antibacterial activity of ethanolic and aqueous extracts of Acacia aroma Gill. ex Hook et Arn. Life Science Journal, 75(2), 191-202.

Aquino, R., Morelli, S., Lauro, M. R., Abdo, S., Saija, A., and Tomaino, A.2001. Phenolic constituents and antioxidant activity of an extract of Anthurium versicolor leaves. Journal of Natural Products, 64 (8), 1019-1023.

Ayoola, G. A., Coker, H. A. B., Adesegun S. A., Adepoju-Bello, A. A., Obaweya, K., Ezzenia, E. C., Atangbayila, T. O. 2008. Phytochemical screening and antioxidant activities of some selected medicinal plants used for malaria therapy in Southwestern Nigeria. Tropical Journal of Pharmaceutical Research, 7 (3), 1019-1024.

Bang, T. H., Suhara, H., Doi, K., Ishikawa, H., Fukami, K., Parajuli, G. P., Katakura, Y., Yamashita, S., Watanabe, K., Adhikari, M. K., Manandhar, H. K., Kondo, R., and Shimizu, K. 2014. Wild mushrooms in Nepal: some potential candidates as antioxidant and ACE-inhibition sources. Evidence-Based Complementary and Alternative Medicine, 2014, 1-11.

Biskup, I., Golonka, I., Gamian, A., and Sroka, Z. 2013. Antioxidant activity of selected phenols estimated by ABTS and FRAP methods. Postepy Higieny I Mediciny Doswiadczalnej, 67, 958-963.

Calvo, M. A., Arosemena, E. L., Shiva, C., and Adelantado, C. 2011.Antimicrobial activity of plant natural extracts and essential oils. Sciences Against Microbial Pathogens; Communicating Current Research and Technological Advances. 1179-1185.

Cujic, N., Savikin, K., Jankovic, T., Pljevljakusic, D., Zdunic, G., and Ibric, S. 2016. Optimization of polyphenols extraction from dried chokeberry using maceration as traditional technique. Food Chemistry, 194, 135-142.

Di Carlo, F. J,, Haynes, L. J., Sliver, N. J., and Phillip, G. E. 1964. Rheticulo endothelial system stimulants of botanical origin. Journal of the Reticulo Endothelial Society, 1, 224-232.

Dornberger, K. and Llich, H. 1982. Screening for antimicrobial and presumed cancerostatic plant metabolites. Die Pharmazie, 37 (3), 215-221.

Dudonne, S., Vitrac, X., Coutiere, P., Woillez, M., Merillon, J. M. 2009. Comparative study of antioxidant properties and total phenolic content of 30 plant extracts of industrial interest using DPPH, ABTS, FRAP, SOD and ORAC assays. Journal of Agricultural and Food Chemistry, 57(5), 1768-1774.

Emami, S. A., Asilii, J., Mohagheghi, Z., Hassanzadeh, M. K. 2007.Antioxidant activity of leaves and fruits of Iranian conifers. Evidence-Based Complementary and Alternative Medicine, 4 (3), 313-319.

Ersam, T., Fatmawati, S., and Fauzia, D. N. 2016. New prenylated stilbenes and antioxidant activities of Cajanus cajan (L.) Millsp. (Pigeon pea). Indonesian Journal of Chemistry, 16, 151-155.

Fatmawati, S., Kurashiki, K., Takeno, S., Kim, Y., Shimizu, K., Sato, M., Imaizumi, K., Takahashi, K., Kamiya, S., Kaneko, S., and Kondo, R. 2009. The inhibitory effect on aldose reductase by an extract of Ganoderma lucidum. Phytotherapy Research, 23 (1), 28-32.

Hassan, A., Rahman, S., Deeba, F., and Mahmud, S. 2009. Antimicrobial activity of some plant extracts having hepatoprotective effects. Journal of Medicinal Plants Research, 3 (1), 20-23.

Hidayati, M. D., Ersam, T., Shimizu, K., and Fatmawati, S. 2017. Antioxidant activity of Syzygium polynthum extracts. Indonesian Journal of Chemistry,17 (1), 49-53.

Janet, J. R., Puzon, M., Rivera, W. L. 2015. Free radical scavenging activity and bioactive secondary metabolites from various extracts of Glinusoppositifolius (L) Aug. DC. (Molluginaceae) roots, stem, and leaves.Asian Pasific Journal of Tropical Disease, 5 (9), 711-715.

Joly, L. G., Guerra, S., Septimo, R. 1987. Ethnobotanical inventory of medicinal plants used by the Guaymiindians in Western Panama Part I.Journal of Ethnopharmacology, 20(2), 145-171.

Kisangau, D. P., Hosea, K. M., Joseph, C. C., and Lyaruu, H. V. M. 2007. In vitro antimicrobial assay of plants used in traditional medicine in Bukoba Rural district, Tanzania. African Journal of Traditional, Complementary and Alternative Medicines, 4 (4), 510-523.

Ling, L. T. and Palanisamy, U. D. 2012. Review: Potential antioxidant from tropical plants. Food industrial processes-methods and equipment. 64-72, Dr. Benjamin Valdez (Ed.), ISBN: 978-953-307-905-9, InTech.

Nostro, A., Germano, M. P., D’Angelo, V., Marino, A., Cannatelli, M. A. N.2000. Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity. Letter in Applied Microbiology, 30(5), 379-384.

Perumal, S., Mahmud, R., Piaru, S. P., Cai, L. W., and Ramanathan, S. 2012. Potential antiradical activity and cytotoxicity assessment of Ziziphus mauritiana and Syzygium polyanthum. International Journal of Pharmacology, 8 (6), 535-541.

Pessoa, A. C. B. P., de Castro, A. C. R., and Gallão, M. I. 2013. Leaf anatomical characterization of two Anthurium Species (Araceae) with a high potential for ornamental purpose. Proceeding VIIth IS on New Floricultural Crops, Acta Hort. 1000, ISHS.

Pourmorad, F., Hosseinimehr, S. J., Shahabimajd, N. 2006. Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plant. African Journal of Biotechnology, 5 (11), 1142-1145.

Rosa, L. H., Machado, K. M. G., Jacob, C. C., Capelkari, M., Rosa, C. A., Zani, C. L. 2003. Screening of Brazilian basidiomycetes for antimicrobial activity. Memorias do Instituto Oswaldo Cruz, 98(7), 1-19.

Rubalya, V. S. and Neelamegam, P. 2015. Selective ABTS and DPPH radical scavenging activity of peroxide from vegetable oils. International Food Research Journal, 22 (1), 289-294.

Satya, V. and Paridhavi, M. 2012. Ethnobotanical, phytochemical and pharmacological review of Anamirta cocculus (Linn) wight and Arn. International Journal of Review in Life Science, 2 (1), 1-6.

Shalaby, E. A. and Sanaa, M. M. S. 2013. Comparison of DPPH and ABTS assays for determining antioxidant potential of water and methanol extracts of Spirulina platensis. Indian Journal of Geo-Marine Sciences, 42 (5), 556-564.

Segura, L., Vila, R., Gupta, M. P., Esposito, A. M., Adzet, T., and Canigueral, S. 1998. Antiinflamatory activity of Anthurium cerrocampanense croat in rats and mice. Journal of Ethnopharmacology, 61 (3), 243-248.

Sultana, B., Anwar, F., and Przybylski, R. 2007. Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia arjuna, Acacia nilotica, and Eugenia jambolana Lam. Trees. Food Chemistry, 104 (3), 1106-1114.

Tadeg, H. 2004. Phytopharmaceutical studies of some selected medicinal plants locally used in the treatment of skin disorders. Pharmaceutics Thesis, School of Pharmacy, Addis Ababa University. 1-148.

Qadir, U., Paul, V. I., and Ganes, P. 2015. Preliminary phytochemical screening and in vitro antibacterial activity of Anamirta cocculus (Linn). Journal of King Saud University-Science, 27, 97-104.

Wiwit, D. F., Ersam, T., Shimizu, K., and Fatmawati, S. 2016. Antioxidant activity of Moringa oleifera extracts. Indonesian Journal of Chemistry, 16(3), 297-301.

World Health Organization. 1979. The selection of essential drugs. Second report of the WHO Expert Committee. WHO Technical Report Series. 641, 1-44.

Zamora, M. M. C. and Pola, C. N. P. 1992. Medicinal plants used in some rural populations of Oaxaca, Puebla and Veracruz, Mexico. Journal of Ethnopharmacology, 35(3), 229-257.

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Published

16-04-2019